Dear Bessie
CD8 is very occasionally expressed on B-cell CLL, I've come across a few
cases. It would appear to have no clinical significance. a few papers have
been published. You might want to check:
B-cell chronic lymphocytic leukaemia with CD8 expression: report of 10 cases
and immunochemical analysis of the CD8 antigen. Mulligan SP, Dao LP, Francis
SE, Thomas ME, Gibson J, Cole-Sinclair MF, Wolf M; Br J Haematol. 1998
Oct;103(1):157-62.
-----Original Message-----
From: Bessie Kam [mailto:bkam@dls.queens.org]
Sent: Friday, October 13, 2000 6:45 AM
To: cyto-inbox
Subject: CD8 postive CLL
Has anyone seen a case that looks like classic CLL (dim kappa+, CD5+, dim
CD20+, CD23+, CD43+, CD10neg, CD3-,CD2-, CD7-, CD4-) BUT with CD8positivity
that coexpresses CD19? What do you think?
thanks, bessie
--
Bessie Kam Email: bkam@dls.queens.org
The Queen's Medical Center, Pathology FAX: 808-547-4045
Phone: 808-547-4271
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