Re: CD14 and CD19 positive cells

From: anpo@mb.ks.se
Date: Thu Mar 09 2000 - 04:32:05 EST


Hi,
which conjugate for CD19 is used? PeCy5 conjugated MAbs often bind to
monocytes giving unspecific double positive results.
Best wishes
Anna

At 15:11 2000-03-07 -0800, you wrote:
>   Hello,   I was wondering if anyone has seen a population  positive for
>both CD14 and CD19. I am staining peripheral blood lymphocytes and  am
>looking at the B cell population. I originally just used CD19 to get the B
>cells. However recently I began using CD3, CD14 to exclude any T cells and
>monocytes. I will use CD56 as well to exclude NK cells. However, I did see
>some  cells that were positive for both CD19 and CD14. Are these cells
>monocytes or  are they B cells. I do want to look at all B cells, my
>question is how can I  find out if these cells are truly B cells or if they
>are monocytes?   Thanks, Annuska Glas
Anna Porwit
Haematopathology Lab.
Department of Pathology
Karolinska Hospital, Stockholm
anpo@mb.ks.se
tel.:+46-851774518
fax.:+46-851775843



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