recovering plasma cells

From: faisal rawas (frawas@hotmail.com)
Date: Wed Oct 27 1999 - 02:31:54 EST


Hello to all,
I would like to know if any one out there been having problems recovering 
plasma cells from bone marrow aspirates when they are submitted to be 
phenotyped by flow cytometry.It seems  that I always recover 20-30% less 
than what the pathologists are estimating with there diff.This is also 
causing me a problem when i try to do CD38/PI staining to estimate the 
S-phase of the plasma cells specially when you end up with less than 10% by 
flow.Any ideas or suggestions to how I can minimize my loss or enrich the 
recovery of plasma cells to match the diff are welcomed.

Faisal Rawas

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