Re: Cell carryover on FacsCalibur with loader

From: John Altman (altman@microbio.emory.edu)
Date: Fri Sep 24 1999 - 07:54:26 EST


Dax Arguello wrote:

> I have noticed a problem with carryover on BD instruments, even when running
> manually. We do mostly stem cell work here, and it's always necessary to run
> bleach and water before the CD34 tubes, since we experience carryover of the
> CD33 PE from the previous tube if we don't. It's not inconvenient, but
> presents a problem with automation using the loader, which may be why we
> haven't gotten one. Before I moved to HCI, I was using a Calibur with a
> loader, and noticed similar carryover. I resorted to running manually, and
> leaving the sample arm open for several seconds between tubes. Pretty easy
> solution, but it does add time to the run.
>

Can't you do the same thing with Loader Manager by adding mixing time between
each tube?

John

--


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John D. Altman, Ph.D.
Emory University Vaccine Center at Yerkes
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