Re: Monocyte depletion

From: Mark A. KuKuruga (kukuru@umich.edu)
Date: Thu Sep 16 1999 - 15:01:22 EST


Robert,
Look at DL Thiele, et al . . . "Phenotype of the accessory cell necessary
for mitogen-stimulated T and B cell responses in human peripheral blood:
Delineation by its sensitivity to the lysosomotropic agent, l-leucine methyl
ester."  Journal of Immunology 131 (5) 1315-2282 (1983).
They describe selective elimination of human monos using the above reagent.
MAK.

Robert Nordon wrote:

> To those working with monocytes,
>
> Are there any drugs (or cytokines/chemokines) that specifically kill or
> inhibit monocyte development in primary cell cultures but are relatively
> non-toxic to other cell types?
>
> Many thanks in advance.
>
> Robert Nordon
> Graduate School of Biomedical Engineering,
> University of NSW.
> Sydney, Australia.

--
Mark A. KuKuruga, Managing Director
University of Michigan Core Flow Cytometry
<http://www.cancer.med.umich.edu/flow_cytometry>
phone: 734-647-3216  fax: 734-936-7376
kukuru@umich.edu



This archive was generated by hypermail 2b29 : Wed Apr 03 2002 - 11:54:00 EST