Re: anti-PE

From: Mario Roederer (Roederer@drmr.com)
Date: Fri Sep 03 1999 - 16:38:12 EST


Ron, we used to use a bi-Anti-PE system:  Stain with PE-antibody.  Wash,
then stain with bi-anti-PE.  Wash, then come in with Av-PE.  The last two
steps can be repeated ad nauseum (until you are naseous).  The anti-PE came
from Peter Lansdorp (at the Terry Fox in Vancouver).  It amplifies very
nicely, but is relatively time-consuming.

mr

>I am doing two color immunofluorescence, and have an antibody that is PE
>conjugated.  PE is not bright enough to visualize alone, so I have to
>amplify with a secondary.  However, I cannot use a goat-anti-mouse, because
>I am using that on the first antibody.  Is there a source for HRP-anti-PE
>that can be used as a secondary?  Less desirable, is HRP-anti FITC.
>
>Thanks
>
>									ron
>
>
>Ronald L. Rabin, M.D.
>Clinical Associate
>Cytokine Biology Unit, Laboratory of Clinical Investigation
>National Institute of Allergy and Infectious Diseases
>National Institutes of Health
>Bldg. 10/Rm. 11N228
>10 Center Drive MSC 1888
>Bethesda, MD   20892-1888
>Phone:  (301) 402-4910
>FAX:      (301) 402-0627
>



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