Dear Jorge and Dan and all, I agree with Dan: we use it in our panel of leukemia phenotyping as a "myeloid" marker. The article by Bene et al. from the European Group for the Immunological Classification of Leukemia's is worth while reading: Blood 92: 596-599, 1998. "The reliability and specificity of c-kit for the diagnosis of acute leukemias and undifferentiated leukemias." Best regards, Dirk Prof. Dirk Van Bockstaele, PhD Head Flow Cytometry Facility Laboratory of Hematology Antwerp University Hospital Belgium > ---------- > Van: darber@smtplink.Coh.ORG[SMTP:darber@smtplink.Coh.ORG] > Verzonden: donderdag 5 augustus 1999 23:07 > Aan: Cytometry Mailing List > Onderwerp: Re:CD117 > > > Although there are some reports of CD117 positive ALL, we have used it on > several hundred acute leukemias and found it to be very specific for > myeloid > lineage. > > Dan Arber > City of Hope > > ____________________Reply Separator____________________ > Subject: CD117 > Author: Jorge Neumann <neumann@santacasa.tche.br> > Date: 8/5/99 6:24 AM > > > > Dear All, > I would like to know the opinion of the group regarding the value > of CD117 in the definition of acute leukemia. > Thanks in advance, > > Jorge Neumann, MD > Flow Lab > Transplantation Immunology > Santa Casa Hospital > Porto Alegre, Brasil > > >
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