I'm making this inquiry on behalf of an investigator working with neutrophil activation who is seeking a marker to be used by flow cytometry which would correlate accurately with degranulation. He has a reference describing the use of a protein called granulophysin (detected on the surface membrane of neutrophils) as a surrogate for degranulation. Any additional information, insights, references, etc., would be greatly appreciated. Thanks, Mary Paniagua, MT(ASCP)SI Robert H Lurie Comprehensive Cancer Center Flow Cytometry Core Facility Northwestern University Medical School Chicago, IL (312)908-1294 m-paniagua@nwu.edu
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