Re: identify murine cell lines

From: Andrew D. Wells, Ph.D. (adwells@mail.MED.UPENN.EDU)
Date: Tue Jun 01 1999 - 12:41:49 EST


>I want to identify murine cell lines (PG13, Mus dunni, NIH3T3) by flow
>cytometry.
>These cells are derived from TK-NIH3T3 but I dont get them stained with
>antibodies against MHC I H-2k (should bind to mouse stains like balb c).
>Has anyone done this before or knows which markers identify these cells as
>murine cells?
>Thanks
>Carsten Lindemann

Carsten,

NIH3T3 cells should have plenty of MHC class I on their surface - I think
you problem is that NIH3T3 cells, and cells from Balb/c mice, are H-2d, not
H-2k.

Hope this helps

AW


Andrew D. Wells, Ph.D.
University of Pennsylvania
Department of Medicine
904 Stellar-Chance Laboratories
422 Curie Boulevard
Philadelphia, PA  19104
(215) 898-1951
(215) 573-2880 (FAX)
adwells@mail.med.upenn.edu



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