Tandem conjugates question

From: Joseph Webster (J.Webster@centenary.usyd.edu.AU)
Date: Wed May 12 1999 - 19:10:11 EST


Hi All,
One group here can't use PE-Cy5 dyes because they bind to the B cells
of NOD mice.
PE alone works fine, so the problem is either Cy5 or the combination;

Does anyone know yet just what the problem is?

Can anyone tell us if APC-Cy7 or other tandem dyes (or Cy7) have the
same problem?

Another question:
Our current lasers are argon (488) and a dye (~600).
I am (wishfully) thinking of going to a 3-laser setup with argon
(488), HeNe (635) and a spectrum laser for choice of UV or other lines.
Any helpful comments &/or suggestions?

	Many thanks, Joseph.

Joseph Webster, Flow Cytometry Facility,
Centenary Institute
Locked Bag No.6, Newtown, NSW 2042, AUSTRALIA.
Ph: 61-2-9565-6110 		Fax: 61-2-9565-6101
e-mail: J.Webster@centenary.usyd.edu.au



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