Notoriously variable cookbook method

From: Donnenberg, Albert (donnenbergad@MSX.UPMC.EDU)
Date: Tue Mar 23 1999 - 18:48:15 EST


> Calman-
> You might like to know that the notoriously variable cookbook method that
> we use for permiabilization will never be exactly duplicated by any other
> lab.  This is because the saponin that we use (Coulter Electronics) came
> with my mentor George Santos' first model ZBI Coulter Counter.  The
> bottle, label intact but frayed, reads "enough for 30,000 determinations."
> The first step in my protocol reads "incubate saponin at room temperature
> for 30 years."
> 
> Please save a glass of champagne for me, even if its that dreadful
> Roederer stuff.
> 
> Albert
> 
> Albert D. Donnenberg, Ph.D.
> Interim Director
> Bone Marrow Transplant Program, UPCI
> 
> Phone: (412) 624-9596
> Fax: (412) 624-9624 
> 



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