What is a labelled cell? (Was - Analysis software)

From: Nicholas Terry (ntflow@odin.mdacc.tmc.edu)
Date: Thu Mar 18 1999 - 08:53:44 EST


It is my impression that the original question had to do with determining what
is a BrdUrd-labelled cell as much as deconvolution of a marginal DNA
distribution. While no software package per se exists in this regard we
described some guidelines to aid in detemining the cut-off between unlabeled G1
and labeled early S-phase (etc) cells which may be of help.
White, R.A., and Terry, N.H.A. A quantitative method for evaluating bivariate
flow cytometric data obtained using monoclonal antibodies to bromodeoxyuridine.
Cytometry, 13: 490-495, 1992.
Best wishes,
Nick

Nicholas Terry, Ph.D.
Experimental Radiation Oncology - Box 66
U.T. M. D. Anderson Cancer Center
1515 Holcombe Blvd.
Houston
Tx 77030, USA           Phone: 713-792-3424     Fax: 713-794-5369
WWW: http://drad52.mdacc.tmc.edu/ 



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