RE:G6PD detection by flow

From: Ulf Gustafsson (ulfgun98@student.umu.se)
Date: Sun Mar 14 1999 - 15:13:13 EST


We used U2000 for analysis of G6PD and Hb. For hemolysis of erythrocyts we
used a solution of 10 uM NADP(M=787.4g/mol), 7mM
merkaptoetenol(D=1.12g/l)and 2.1mM Na-EDTA(M=372.24g/mol).For cleaning the
bloodcells, 0.9% NaCl was used.
After centrifugation, hemolyssolution was mixed with Potassiumcyanid whereas
the absorbtion of Hb was determed with Corning 252. When knowing the
absorbation you can calculate the cocentration. 
This formula helps you calculate the activity of G6PD (see attached file).

Carina Kullman
Dept. Medicin-odontology
University of Umea
email: caakun98@student.umu.se




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