This question is posted for a colleague. Please respond directly to him at jbleesing@mail.cc.nih.gov Thank you. Is there a human counterpart to the mouse B220 (CD45R isoform). If not could the anti-mouse B220 MoAb be used in humans, assuming there is sufficient homology. The application would be to use this as a marker of the double-negative T-cells in ALPS patients (similar to the mouse MRL/lpr model) Margaret R. Brown NIH, Immunology, Clinical Pathology Bldg10/2C410 Bethesda, MD 20892
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