Re: Dilution of whole blood

From: Te Chih Liu (liutc@pacific.net.sg)
Date: Mon Mar 08 1999 - 11:01:31 EST


>I mainly uses the cytometry for immunophenotyping of whole blood or bone
>marrow samples for haematological diseases identification (e.g.
>leukaemia, CLPD). Before the staining of blood with clones, I will
>adjust the cell concentration to a desirable count. I currently use the
>self-prepared pH 7.4 PBS with 10% albumin for dilution. 
>1. Does anyone use other type of dilutent?
>2. Do interferences occur if the dilutent contains preservative e.g.
>Coulter IsoFlow?

My personal preference is for a culture medium of some sort e.g RPMI - it 
keeps the cells stable for a longer time.

Te-Chih Liu
NUH Haematology
Singapore



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