Fibre optics.

From: R.Wadley (s9803537@pop3.unsw.edu.au)
Date: Sun Feb 28 1999 - 19:40:04 EST


	Dear All,

	I manage a lab with 3 laser based cell analysis instruments.  They include
a MoFlo high speed cell sorting cytometer,  a Compucyte Laser Scanning
Cytometer & a Bio-Rad Confocal Microscope.  The confocal runs an optical
fibre to deliver its laser light from the laser to the instrument.  This
seems to becoming more popular with confocal microscope systems.  I can see
advantages in this type of system for my lab.  In a big lab with several
machines within a reasonable radius you could have a battery of different
lasers & use the optical fibre setup to mix & match across different
machines depending on the requirements at the time.  Any thoughts?  
	One of the disadvantages is that confocals & scanning cytometers (both use
microscopes & slides) tend to use very low MW output lasers (~15 MW), where
flow cytometers use much higher output lasers (100 - 300 MW).
	I understand that another problem is the loss of coherence due to the way
light is transmitted along an optical fibre, & a loss of power, as little
as 10% of the output of the laser reaches the end of the fibre(?).
	If the problems could be resolved, it could save on duplicating lasers on
each piece of equipment, & mean there was more money for a wider variety of
lasers to cover a wider range of applications.  

	Regards
	
	Rob W.


	
R. Wadley, B.App.Sc, M.L.S
Laboratory Manager
Cellular Analysis Facility
School of Microbiology & Immunology
UNSW, New South Wales, Australia, 2052
Ph (BH) 	+61 (2) 9385 3517
Ph (AH)	+61 (2) 9555 1239
Fax 	+61 (2) 9385 1591
E-mail	r.wadley@unsw.edu.au
www	http://www.unsw.edu.au/clients/microbiology/CAF.html
	(Under development)



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