Re: Apoptosis

From: jayaramans@msnotes.wustl.edu
Date: Fri Feb 19 1999 - 10:36:19 EST


Rick Meister,

Here are the answers for your questions:

1. Jurkat clone E6-1 (available from ATCC and also from many Immunology
labs),grows very well and are very sensitive to apoptosis by irradiation
(2000 rads) or treatment with anti-Fas antibody (20 ng/ one million
cells)or C2-ceramide (40 micromolar concentration). This cell line is also
sensitive to many other drugs and agents that induce apoptosis. It is
reliable and will serve as a positive control.

2. You can pronounce the word apoptosis as you feel like. In a meeting on
apoptosis in San Diego two years ago, this issue was discussed. It was
concluded that you can pronounce it as you wish.

With regards,
Jay



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