Mitotic Index is a microscopic evaluation of the proliferation activity of a tissue (e.g. a breast carcinoma). By counting the cells in mitosis in ten fields at 40X (High Power Fields - HPF) you will get the Mitotic Index (1 per 10 HPF, 6 per 10 HPF and so on). The Mitotic Index is a part of the Tumor Grading with others index such the tumor dimension, the presence/absence of vessels, the chromatine pattern and so on. The Index is not related to the DNA content, it is a simply count . It is widely used because it is simply to achieve, you just need a microscope. Edoardo Colombo MD Flow Lab Dept. of Pathology Valduce Hospital Como, Italy
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