Dear flowers, Is there anybody in the group who has any experience with permanent CD4 downregulation in vivo? In our model we have observed a prominent CD3+CD4- T cell subset several weeks after injecting sorted CD4+ cells into SCID mice. Jiri Sinkora Dept. Immunology and Gnotobiology Inst. Microbiology Acad. Sci. Czech Rep. tel.: + 420 441 478212 fax: + 420 441 478264 e-mail: cyto@biomed.cas.cz
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