membrane-labeling

From: Andreas Simm (simm@klin-biochem.uni-wuerzburg.de)
Date: Fri Jan 22 1999 - 03:00:56 EST


Hello flowers,
I repeat my question as I did not get the original mail
from Wednesday and maybe, this mail was lost. Excuse
me, if you get this mail a second time!

A colleague want to make cell fusions. For this purposes, the 
membane of one cell population (B-cells) should be labelled
for later analysis of the fusion by flow cytometry.

I proposed pkH-26 from Sigma for membrane labeling, and in 
addition, the labeling of the DNA of the second cell population with 
Hoechst 33342. Cells from positive fusions should have blue nuclei and 
red membranes (suitable for the analysis by flow cytometry).
Is this choice acceptable or does anybody knows better alternatives?

We would be happy for any references.

Thanks 

Andreas


PD Dr. Andreas Simm
Institut für klinische Biochemie und Pathobiochemie
Versbacher Str. 5
97078 Würzburg

Tel.:   0931-201-3479
FAX.: 0931-201-3153



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