Dear Marck, ---------- From: Marc Jacobsen[SMTP:jacobsen@mailer.uni-marburg.de] Sent: Segunda-feira, 11 de Janeiro de 1999 15:46 To: cyto-inbox Subject: CD4 positive but CD3 and CD14 and CD16 and TCRalpha/beta and TCRgamma/delta negative cells Dear colleagues, has anyone experience with such a cell type? We found it in the cerebrospinal fluid of a patient suffering herpes enzephalitis. The cells are up to 10-times bigger than T cells and express CD4 on their surface. Maybe it is a kind of tumor cell? Thanks in You should consider that monocytes macrophages are also positive for CD4. They can loose CD14 in some activation process. Did you test any other monocytes/macrophages marker, as for example CD11C and CD15? advance Marc Marc Jacobsen MZ Nervenheilkunde - Neurologische Klinik mit Poliklinik Rudolf-Bultmann-Str.8, 35039 Marburg, Germany, Fax +49 6421 28 7055, Phone +49 6421 28 2678
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