MoAb against IgM Fab

From: Nick Acquarola (nickacqu@rph.health.wa.gov.au)
Date: Wed Jan 06 1999 - 00:10:55 EST


I am looking for a monoclonal antibody (any species) against the Fab portion of human IgM.
Products that I have found either have antibodies against the Fc portion or do not supply this 
information, assuming that they would be against Fc.
Do they exist ??.

I don't wish to use DTT or 2-ME (for obvious reasons) or use affinity purification techniques as I 
am playing with small volumes (<100 ul).

I wish to use it to block serum IgM from binding, but keep IgG free.

The antibody does not need to be labelled.


Any information would be grateful. 



Thankyou



Nick Acquarola
Senior Medical Scientist
Clinical Immunology
Royal Perth Hospital
Perth, Western Australia



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