FW: CD2 Receptor Number on Human Lymphocytes and or Jurkat cells

From: Barren, Phil (BarrenP@MedImmune.com)
Date: Thu Jan 29 1998 - 09:50:33 EST


For those of you are interested.
Thanks to those that responded

Pb

> ----------
> From: 	Lynn Dustin[SMTP:dustinlb@SLU.EDU]
> Sent: 	Monday, January 26, 1998 11:52 AM
> To: 	Barren, Phil; cytometry@flowcyt.cyto.purdue.edu
> Subject: 	Re: CD2 Receptor Number on Human Lymphocytes and or
> Jurkat cells
> 
> I am forwarding the response below from Michael Dustin.  Hope it's
> helpful.
> Lynn Dustin,Ph.D.
> Assistant Professor
> Molecular Microbiology and Immunology
> St. Louis University
> 
> >CD2 on Jurkat is variable with anywhere from 80,000-200,000
> sites/cell
> >depending upon the clone.  The ATCC cells are around 80,000 by our
> >measurements.  The average density of CD2 on resting peripheral blood
> T
> >cells is 50,000 per cell.  Since there are two populations that
> differ by
> >2.5 fold the actual number on any single cells should be ~30,000 or
> 70,000
> >depending on whether they are memory of naive phenotype.
> 
> >Michael L. Dustin, Ph.D.
> >Assistant Professor of Pathology
> >Washington Unversity School of Medicine
> >Department of Pathology
> >Box 8118
> >660 S. Euclid Ave
> >St. Louis, MO 63110
> 
> 
> 
> >>FLOWers
> >>
> >>Does anyone happen to know the CD2 receptor number on human
> lymphocytes
> >>or on Jurkat cells??
> >>
> >>Thank you in advance for your help
> >>
> >>Philip Barren
> >
> 
> 



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