In reference to the recent article: Goodell M et al. "Dye efflux studies suggest that hematopeitic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species"; Nature Medicine Vol.3 No.12, December 1997. For the stem cell experts amongst us, how do feel this impacts the thinking when performing either stem cell purification (for autologous reconstitution) or stem cell enumeration? As these cells are more primitive than the CD34+ stem cell, should we infer that they may be better suited to hematopoietic reconstitution? Thanks for any thoughts you'd like to share. -- Keith Bahjat Graduate Assistant University of Florida College of Medicine Gainesville, Florida kbahjat@ufl.edu
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