I have found this rare artifact on at least one person with thyroid
dysfunction. Maybe there is a correlation.
Maryalice
> Thanks to everyone who posted a responese to my initial question on
> CD4/8 double postive staining in a female with hypothyroid. I'd just
> like to update everyone. Turns out that it was a plasma artifact
> causing the double labeling. Washing the cells removed the double
> positive artifact completely. Now I have another question. In 3 of
> the responses I received they also saw this staining artifact in
> people on synthetic thyroid hormone for hypothyroid. This seems kind
> of odd (at least to me) for 2 relatively rare events to coincide like
> this. I checked the literature but unfortunately flow panels are not
> routinely run on people with hypothyroid. If anyone has any ideas on
> this possible(?) correlation please let me know. This is not a
> pressing issue, just one of those little questions I like to play
> with.
>
> Thanks again,
>
> Mike Koratich
> USARIEM
> mkoratich@natick-ccmail.army.mil
Maryalice Stetler-Stevenson
Director Flow Cytometry Unit
Laboratory of Pathology, NCI, NIH
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