B cells

From: erik a gamerl (egamerl@unlgrad1.unl.edu)
Date: Thu Oct 16 1997 - 22:30:49 EST

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The 14.8 antibody reacts with an exon A-dependent epitope of CD45.  
Currently, I'm studying B cells in the bone marrow, spleen, and 
peritoneal cavity of MRL/lpr mice and BALB/c mice.  I have examined the 
recent literature and I understand that similar studies use 
CD45R/B220, RA3-6B2.  Will the 14.8 antibody give me the sensitivity 
necessary to examine to various B cell subpopulations?

Any suggestions would be appreciated.

Thanks,


Erik Gamerl
University of Nebraska-Lincoln

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