Hi flowers, We have been asked by our pediatrics department to help confirm the diagnosis of Langerhans cell granulomatosis (formerly histiocytosis X) in a 5 yr. old boy. Does anybody know whether flow analysis of peripheral blood is of any help and what findings to expect. Our pediatric specialist belive that a prominant feature of the disease is disturbance in numbers of CD4+ and CD8+ lymphocytes and natural killer cells. I cannot find this confirmed in the literature. Any suggestions are welcome. Regards Ulrik Ulrik Sprogoe-Jakobsen Dept. Clinical Immunology Odense University Hospital DK-5000 Denmark Phone: +45 6541 3576 fax: +45 6612 7975
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