Dear all can anyone shed some light on a possible naive question. Can we call CD8 cells which lose CD62L expression memory cells? Conversely, are CD8 cells that express CD62L of a naive phenotype?...or would this be an oversimplification. I ask as someone has shown me data looking at TCR V beta expression on CD8+CD62L+ cells and said these were naive cells. Would this make sense? Comments would be appreciated...many thanks Clive Gray Stanford
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