fate of cultured progenitors

From: Ralph Bohmer (ralph.bohmer@es.nemc.org)
Date: Thu Jul 31 1997 - 07:34:35 EST


Could anyone help me find good references dealing the following subject:

Proliferating hemopoietic progenitors in culture (semi-solid or liquid) 
differentiate to a certain point, then they get stuck and apoptose, I guess, 
even with all relevant cytokines present (?) 

How far do the cells from various lineages get ?
How do they die ?
How can death at this point be manipulated ?
                                          
Many thanks in advance

Ralph M. Bohmer
Mew England Medical Center                          



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