Re: BETTER RED THAN VIOLET? the colur bias...

From: Hazel Davey (hlr@aber.ac.uk)
Date: Thu Jun 26 1997 - 08:31:44 EST


On 25 Jun 97 at 22:38, Bob Ashcroft wrote:

> Is the He-Ne path of higher wavelength excitation superior to the
> He-Cd (or Hg arc) path of shorter wavelength excitation?

> Can you give me your tuppence-worth on this?

Generally sppekaing, red excitation has an advantage over UV and 
even 488 nm excitation in that there is less autofluorescence from 
the biological material that you are trying to study. One of the 
exceptions to this rule is plant material of course. Obviously the 
best and most flexible path is for new dyes to be developed for all 
of the wavelengths that we would wish to use. I'm not convinced that 
UV has been overlooked in favour of red excitaion but that may 
be because I'm looking around desperately for more red dyes to use 
with a laser diode-based instrument at the moment...

> Can you give me your tuppence-worth on this?

Well in local currency that's my 2c (ceiniog, not cents of course!)

Haze
----------------------------------------------------------
|            Hazel Marie Davey   hlr@aber.ac.uk          |
|Sefydliad y Gwyddorau Biolegol*Inst. Biological Sciences|
|Prifysgol Cymru               *      University of Wales|
|     ABERYSTWYTH, Ceredigion, CYMRU / WALES SY23 3DA    |
|            http://pcfcij.dbs.aber.ac.uk/index.htm      |



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