> >Happy year year to one and all. > >I have a bone marrow biopsy on a 63 yr old male with severe peripheral >pancytopenea. Biopsy is atypical lymphoid infiltrate consistent with NHL >small cleaved cell. Light scatter shows a single population of small >lymphocytes. The phenotype is CD5-, CD19+, CD22+, CD10-, CD20+, CD25-, >CD23-, CD103-, CD11c-, kappa bright positive, lambda negative. Seems to fit >best with follicular lymphoma except for the CD10 negativity. I wonder what >others of you may think about this phenotype? > >Thanks, > >Brent Dorsett >Director, Special Pathology Laboratories, Lenox Hill Hospital, NYC > >Hi! The immunophenotype may be consistent with immunocytoma alt. marginal cell lymphoma according to REAL classification. Most of the FCC NHL should be CD10+!. Happy New New Year to everybody! Anna Porwit MD, PHD Haematopathology, Karolinska Hospital, Sweden >
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