CD22

B CELLS

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
HD239 (B3)	Purified	100 tests	Freeze-dried	COULTER CLONE		6603613
IgG2b (mouse)
* SJ10.1H11	Purified	0.2 mg	Freeze-dried			IM0715
IgG1 (mouse)*TH*	Purified	100 tests	Liquid	IOTest		IM0716
	FITC	100 tests	Liquid	IOTest		IM0779
	PE	100 tests	Liquid	IOTest		IM1835
CYTO-STATS

The CD22 antigen (BL-CAM) is a transmembrane glycoprotein of the immunoglobulin superfamily. It may be expressed as two different isoforms: the a form (130 kDa) and the b form (140 kDa). It is a B cell restricted antigen expressed in the cytoplasm of B cell progenitors and on the surface of mature B cells. CD22 expression is lost after B cell activation, prior to the plasma cell stage. It is absent from peripheral blood T cells, granulocytes, monocytes. B3 antibody binds to an epitope located within the first Ig-like domain of CD22 antigen. HD239 (B3) antibody was evaluated during the Fourth International Workshop on Human Leukocyte Differentiation Antigens. Workshop. SJ10.1H11 antibody was evaluated during the Third Workshop.

---

---

© Coulter International Corporation, 1996. All rights reserved. Copyrights and Trademarks


Products are available FOR RESEARCH USE ONLY (RUO). Unless indicaed FOR IN VITRO DIAGNOSTIC USE (IVD)