CD3

T CELLS

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
UCHT1	Purified	0.2 mg	Freeze-dried			IM1304
IgG1 (mouse)	Purified	100 tests	Liquid	IOTest		IM1280
	Purified	100 tests	Freeze-dried	COULTER CLONE	IVD	6604629
	Biotin	0.2 mg	Freeze-dried			IM1301
	FITC	100 tests	Liquid	IOTest		IM1281
	FITC	100 tests	Freeze-dried	COULTER CLONE	IVD	6604625
	PE	100 tests	Liquid	IOTest		IM1282
	RD1	100 tests	Liquid	COULTER CLONE	IVD	6604627
	PE-Cy5	100 tests	Liquid	IOTest		IM1371
X35	Purified	0.2 mg	Freeze-dried			IM0178
IgG2a (mouse)
CYTO-STATS

The CD3 antigen is a complex of 5 invariable polypeptidic chains ; g, d, e, z and h whose molecular weights are respectively: 25-28, 20, 20, 16 and 22 kDa.The z chain frequently occurs in the CD3 complex as disulphide linked homodimer. CD3 is part of a bigger complex which includes the T Cell Receptor (TCR). It is expressed by mature T cells and by thymocytes. T cell activation can be induced when foreign antigen is presented to the TCR through MHC complex. These antibodies also have a mitogenic effect on T lymphocytes. They do not react with those T cells lacking the TCR. X35 and UCHT1 antibodies react with the e-chain of the CD3 complex. UCHT1 antibody was evaluated during the First International Workshop on Human Leukocyte Differentiation Antigens. X35 was evaluated during the Third Workshop.

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