Re: Kappa/lambda ratios

Bruce Davis, MD - Clinical Pathology (bdavis@beaumont.edu)
Mon, 20 Nov 1995 12:57:15 -0500 (EST)

There is very likely a lymphoproliferative disorder.

Bruce H. Davis, M.D.

On Fri, 17 Nov 1995, Tom Mchugh wrote:

> What are the opinions as to the importance of an inverted kappa:lambda
> ratio? We sometimes see cells in peripheral blood and lymph nodes that
> when phenotyped show more lambda positive cells than kappa. When the
> kappa: lambda ratio is over 4 or 5 there is apparently some general
> agreement that this suggests a monoclonal population. Is the same true
> if the ratio is 0.25 or less?
>
> Thanks
>
> Tom McHugh
> Department of Laboratory Medicine
> University of California at San Francisco
> mchugh@labmed.ucsf.edu
>