HLA Class I MAbs

A.C. JOHNSON (mrpacj@south-01.novell.leeds.ac.uk)
Fri, 20 Sep 1996 17:21:39 GMT0BST

Andrew Johnson ~ Clinical Scientist ~ National Blood Service.

I'm involved in a study of class I HLA molecules and I am trying to
find monoclonal antibodies that bind to different epitopes on the
molecule, so that it will be possible to completely cover the
molecule.

Commercially very few clones are available and of these, most
recognise the same site as W6/32. A number of monoclonal workshops
have been involved in this area and as a result a large number of
monoclonals have been identified.

Has anybody been involved in these workshops, or do they know of a
potential source of Class I HLA specific monomorphic MABs ?


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