Map 4-Antibodies

TCR Vbeta11 (TCRBV11S1)

Clone & Isotype Conjugate Size Format Line Part Number
C21 Purified 0.1 mg Freeze-dried TCR Line IM1582
IgG2a (mouse) Biotin 0.1 mg Freeze-dried TCR Line IM2018
FITC 50 tests Liquid TCR Line IM1586

Two Vb11 sequences (PL3.12, and PH15 sequences) are described in the literature differing only in their leader sequence, and, therefore, results in the same mature protein.The C21 antibody recognizes the gene product of these sequences and stains 0.4 to 0.9% of peripheral CD3 positive cells in normal blood. An invariant Va24/Vb11 T cell receptor is expressed in all individuals by clonally expanded CD4- CD8- T cells, reactive to bacterial antigens.
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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu