HLA-DR

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
B8.12.2	Purified	0.2 mg	Freeze-dried			IM0108
IgG2b (mouse)	Biotin	0.2 mg	Freeze-dried			IM0261
	Purified	100 tests	Liquid	IOTest		IM0462
	FITC	100 tests	Liquid	IOTest		IM0463
	PE	100 tests	Liquid	IOTest		IM0464
Immu-357	FITC	100 tests	Liquid	IOTest		IM1638
IgG1 (mouse)	PE	100 tests	Liquid	IOTest		IM1639
	PE-Cy5	100 tests	Liquid	IOTest		IM1849
H279 (I2)	Purified	100 tests	Freeze-dried	COULTER CLONE		6602142
IgG2a (mouse)	FITC	100 tests	Freeze-dried	COULTER CLONE		6602924
	RD1	100 tests	Liquid	COULTER CLONE		6602920
BL2	Purified	0.2 mg	Freeze-dried			IM0109
IgG2b (mouse)

The recognized epitope is a monomorphic determinant of human HLA class II molecules with estimated molecular weights of 29-34 kDa. These molecules are found on Antigen-Presenting Cells (APC), i.e. B lymphocytes, monocytes, macrophages, and thymic epithelial cells. They are also expressed on activated T cells, but not on granulocytes, platelets, and red blood cells. The I2 antigen is absent from some homozygous typing cells which are DR7+ or DR11+. Resting T cells or endothelial cells that do not normally express these molecules can be induced to express them. These molecules are involved in cellular interactions among immuno-competent cells. I2 antibody was evaluated during the Fifth International Workshop on Human Leukocyte Differentiation Antigens.

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu