CD126

Interleukin 6 receptor (a chain)

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
M91	Purified	0.2 mg	Freeze-dried			IM1434
IgG1 (mouse)	PE	100 tests	Liquid	IOTest		IM1979

The CD126 antigen is the human IL-6 receptor a chain (gp80). In peripheral blood it is detectable on monocytes, on granulocytes, and on CD4+ T lymphocytes. This antigen is also expressed by epithelial cells. M91 antibody recognizes membrane and soluble form of IL-6.R a chain.It binds to the amino terminal immunoglobulin domain of IL-6.R. It binds to IL-6/IL-6.R complexes and IL-6/IL-6R/gp130 complexes. It is a non-blocking antibody. It is suitable for Western blot. M91 antibody was evaluated during the Fifth International Workshop on Human Leukocyte Differentiation Antigens.

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu