Map 4-Antibodies

CD106

CD106

VCAM-1

Clone & Isotype Conjugate Size Format Part Number
1G11 Purified 0.2 mg Freeze-dried IM1244
IgG1 (mouse)

The CD106 antigen is a 90 kDa membrane protein which is present on activated endothelial cells, tissue macrophages, dendritic cells and bone marrow fibroblast. It is involved in the adhesion of lymphocytes, monocytes and eosinophils to activated endothelium. Vascular Cell Adhesion Molecule-1 (VCAM-1) is an adhesion molecule which binds to integrin a4/b1 (VLA-4) and integrin a4/b7 on lymphocytes. 1G11 antibody inhibits T lymphocyte adhesion to TNF-stimulated endothelial cells. It has been evaluated in Fifth International Workshop on Human Leukocyte Differentiation Antigens.
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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu