Map 4-Antibodies

CD80

B-CELL SUBSET

Clone & Isotype Conjugate Size Format Line Part Number
MAB104 Purified 0.2 mg Freeze dried IM1449
IgG1 (mouse) FITC 100 tests Liquid IOTest IM1853
PE 100 tests Liquid IOTest IM1976

The CD80 antigen (B7, BB1) is a highly glycosylated single-chain protein. Its extracellular domain consists of two Ig-like domains. This 60 kDa molecule serves as the ligand for two structurally similar molecules expressed on T lymphocytes, CD28 and CTLA-4. CD80 antigen is expressed on in vitro activated B cells. It is not expressed on the majority of resting B cells from peripheral blood but identifies a subpopulation of B cells that has been previously activated. The antigen is also expressed by HTLV-1 transformed T cells.
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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu