CD79a

B CELLS

Clone & Isotype	Conjugate	Size	Format			Part Number
HM47	Purified	0.2 mg	Freeze dried		(in dev’t)	IM2035
IgG1 (mouse)

The CD79a molecule (MB-1, Iga) is part of the MB-1/B29 disulfide-linked heterodimer which is non-covalently associated with membrane immunoglobulins (Igs) to build the B Cell antigen Receptor (BCR) complex. CD79a is a 32-33 kDa glycoprotein and belongs to the Ig superfamily of surface antigens. CD79a protein is expressed specifically through out B cell differentiation. It appears early in ontogeny, probably before expression of cytoplasmic µ-chain, and is present in the cytoplasm of plasma cells. HM47 antibody reacts with a specific cytoplasmic epitope of the CD79a molecule. It was evaluated during the Fifth International Workshop on Human Leukocyte Differentiation Antigens.

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu