CD62P (not available in USA)

P SELECTIN

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
CLBThromb/6	Purified	0.2 mg	Freeze-dried			IM1315
IgG1 (mouse)	Purified	100 tests	Liquid	IOTest		IM0767
	FITC	100 tests	Liquid	IOTest		IM1164
	PE	100 tests	Liquid	IOTest		IM1759

The CD62P antigen, also called LECAM-3 or P-selectin, is a 140 kDa molecule that mediates adhesion of neutrophil and monocyte to activated platelets and endothelial cells. It is expressed in the a-granules of the platelets and in the Weibel-Palade bodies of endothelial cells. Upon activation or thrombin stimulation, the antigen is translocated to the cell surface in both types of cells. Its ligands are PSGL-1 on granulocytes and CD34. CLBThromb/6 antibody recognizes an antigen preserved after platelet fixation. It inhibits platelet adhesion to eosinophils in cell adhesion assays. CLBThromb/6 antibody was evaluated during the Fifth International Workshop on Human Leukocyte Differentiation Antigens.

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu