CD62E

ELAM-1

Clone & Isotype	Conjugate	Size	Format			Part Number
1.2B6	Purified	0.2 mg	Freeze-dried			IM1243
IgG1 (mouse)
* 4D10	Purified	100 tests	Freeze-dried			IM0805
IgG2a (rat)

The CD62E antigen, also called LECAM-2 or E-selectin, is a 115 kDa molecule which mediates neutrophil, eosinophil and monocyte adhesion to vascular endothelium. It is expressed by activated endothelial cells. Sialyl LewisX acts as a ligand for ELAM-1. 4D10 antibody is not a blocking antibody. 1.2B6 antibody partially inhibits the CD62E adhesion of eosinophils and of neutrophils to endothelial cells. Both antibodies were evaluated during the Fifth International Workshop on Human Leukocyte Differentiation Antigens.

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu