CD51

alpha-Chain of VNR

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
AMF7	Purified	0.2 mg	Freeze-dried			IM0770
IgG1 (mouse)	FITC	100 tests	Liquid	IOTest		IM1855
69-6-5	Purified	0.2 mg	Freeze-dried			IM1603
IgG2a (rat)

The CD51 antigen is the 140 kDa integrin aV-chain, consisting of a disulfide-linked subunit of 125 kDa and a smaller one of 25 kDa, non-covalently associated with the integrin b3 chain also known as GPIIIa or CD61 molecule. This complex is known as the vitronectin, the fibrinogen and the von Willebrand's factor receptor. It is expressed by platelets and megakaryocytes, by some B cells and by endothelial cells. AMF7 antibody is weakly blocking. 69-6-5 is a strongly blocking antibody in cell antigen assays. AMF7 antibody was evaluated during the Fifth International Workshop on Human Leukocyte Differentiation Antigens.

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu