CD50

ICAM-3

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
HP2/19	Purified	0.2 mg	Freeze-dried			IM1600
IgG2a (mouse)	PE	100 tests	Liquid	IOTest		IM1601

The CD50 antigen is a 124 kDa molecule expressed by leukocytes and a wide variety of cells, but not by endothelial cells, platelets or erythrocytes. It is known as the InterCellular Adhesion Molecule-3 (ICAM-3) and interacts with LFA-1 in cellular adhesion. The HP2/19 antibody blocks adhesion which is directly or indirectly mediated by ICAM-3. This antibody is co-stimulating in CD3-dependent proliferation. HP2/19 antibody was evaluated during the Fifth International Workshop on Human Leukocyte Differentiation Antigens.

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu