Map 4-Antibodies

CD49f

VLA-a6 CHAIN

Clone & Isotype Conjugate Size Format Part Number
GoH3 Purified 0.2 mg Freeze-dried IM0769
IgG2a (rat)

The CD49f antigen (gpIc) is a disulfide-linked large subunit of 120 kDa and small subunit doublet of 30/31 kDa, called integrin a6-chain. When non-covalently associated with the 130 kDa integrin b1-chain (CD29 molecule), it forms the VLA-6 complex (GPIc/IIa). It is known as the laminin receptor. It is found on platelets and megakaryocytes. It is weakly expressed by a subpopulation of T lymphocytes. It can be associated with the integrin b4-chain forming the a6/b4 complex. GoH3 antibody inhibits the adhesion of platelets to laminin. It is not suitable for Western blot. GoH3 antibody was evaluated during the Fourth International Workshop on Human Leukocyte Differentiation Antigens.
Home Contents Previous Next
© Coulter International Corporation, 1996. All rights reserved. Copyrights and Trademarks


Products are available FOR RESEARCH USE ONLY (RUO). Unless indicaed FOR IN VITRO DIAGNOSTIC USE (IVD)
Home Page Table of Contents Sponsors Web Sites
CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu