CD49b
VLA-a2 CHAIN
Clone & Isotype | Conjugate | Size | Format | Line | | Part Number |
|
Gi9 | Purified | 0.2 mg | Freeze-dried | | | IM0717 |
IgG1 (mouse) | FITC | 100 tests | Liquid | IOTest | | IM1425 |
|
|
The CD49b antigen (GPIa) is the 170 kDa integrin a2 chain which is non-covalently associated with the 130 kDa integrin b1-chain (CD29 molecule) forming the VLA-2 complex (GPIa/IIa). It is known as the collagen receptor. It is expressed by platelets, activated T cells and thymocytes. Gi9 antibody reacts with the molecule carrying the Br(a) as well as the Br(b) alloantigen. This antibody inhibits the adhesion of platelets to collagen. CD49b detects human alloantibodies (anti-Br a,b) against VLA-2 by MAIPA assay. It is not suitable for Western blot analysis. Gi9 antibody was evaluated during the Fourth International Workshop on Human Leukocyte Differentiation Antigens.

© Coulter International Corporation, 1996. All rights reserved. Copyrights and Trademarks
Products are available FOR RESEARCH USE ONLY (RUO). Unless indicaed FOR IN VITRO DIAGNOSTIC USE (IVD)
CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories
and distributed free of charge as an educational service to the cytometry community.
If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL,
Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu
EMAIL robinson@flowcyt.cyto.purdue.edu