Map 4-Antibodies

CD46

MEMBRANE COFACTOR PROTEIN (MCP)

Clone & Isotype Conjugate Size Format Part Number
J4.48 Purified 0.2 mg Freeze-dried IM0846
IgG1 (mouse)

The CD46 antigen is a 66-56 kDa non-disulfide-linked dimeric protein with O-linked glycosylation. It is known as the Membrane Co-factor Protein (MCP), a cofactor which binds to C3b or C4b, allowing their degradation by a serine protease of the plasma, the factor I. It is expressed on thymocytes, T cells, B cells, monocytes, granulocytes, Natural Killer (NK) cells, platelets, endothelial cells, epithelial cells, fibroblasts, but not on erythrocytes. J4.48 antibody was evaluated during the Fourth International Workshop on Human Leukocyte Differentiation Antigens.
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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu