CD40

MATURE B CELLS

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
MAB89	Purified	0.2 mg	Freeze-dried			IM1374
IgG1 (mouse)	PE	100 tests	Liquid	IOTest		IM1936

The CD40 antigen is a glycosylated phosphoprotein. It is a member of the Tumor Necrosis Factor Receptor (TNFR) superfamily and contains four cysteine-rich repeats. Its molecular weight is about 44-48 kDa. It is present on all mature B lymphocytes, but not on plasma cells. It is strongly expressed by interdigitating cells and also by some epithelial cells and follicular dendritic cells. Co-culture with MAB89 and IL-4 leads to long term B cell proliferation.

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu