CD38

ACTIVATED T CELLS

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
T16	Purified	0.2 mg	Freeze-dried			IM0366
IgG1 (mouse)	FITC	100 tests	Liquid	IOTest		IM0775
	PE	100 tests	Liquid	IOTest		IM1832
CYTO-STATS

The CD38 antigen is a type II integral membrane glycoprotein, with the NH2-terminus inside the cytoplasm.Its molecular weight is about 45 kDa. It is expressed on activated T and B cells, monocytes, Natural Killer (NK) cells, plasma cells and medullary thymocytes. It is also present on terminally differentiated B cells, and early B cells. However, most mature resting peripheral lymphocytes of both B and T lineages, do not express CD38 antigen. Its tissue distribution appears to be dependent on the differentiation and activation of the cell. It is used as a marker to study T and B lymphocyte activation. T16 antibody was evaluated during the Third International Workshop on Human Leukocyte Differentiation Antigens.

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu